SMS has a thirty nine member General Council (GC) of which eleven members are elected to form Executive Committee (EC). The eleven member Executive Committee consists of a Chairperson, Secretary, a treasurer and eight EC members. Members of General council and Executive Committee are renowned personalities of health, HIV/AIDS and development field in Bangladesh and have very good expertise and long experiences in their respective field of work. The GC meeting held once in a year for deciding on major policy and organizational governance issues and to form new Executive committee in every three years. The Executive Committee meets once every three months to review progress, future plans and develop policy framework. The staff members are responsible for implementation of the project under the policy framework and supervision of the Executive Committee through the Executive Director.
Executive Director of the organization is accountable to the Executive committee. There is different category of staff at different layers. Senior Management Team of SMS consists of Coordinators of different projects under the Leadership the Executive Director. Management level of SMS includes staff up to officer levels of different projects. Under the leadership of the Executive Director about 65 experienced and qualified regular and part time staffs are working in different projects of SMS.